3. Results
Double-click node for Gene Effect, edge for Correlation
New to Correlate?
Click Test Genes and then Run ▶
(both in "2. Input Genes")
Tip: Click Correlate to view a scatter plot, or By Tissue for tissue breakdown. You can adjust axis ranges, highlight specific cell lines, and download as PNG or CSV.
| Gene1 | Gene2 | Correlation | Slope | N | Cluster | Analyze |
|---|---|---|---|---|---|---|
| Run analysis to view correlations | ||||||
Mean (All) = all cells, Mean (Filt) = filtered cells. * indicates genes from your input list (Design mode).
| Gene | Cluster | Mean Effect | SD |
|---|---|---|---|
| Run analysis to view clusters | |||
Note: Differential gene effects may reflect selection bias (e.g., mutations enriched in certain cancer types) rather than direct functional consequences of the mutation. Consider filtering by lineage to control for tissue-specific effects.
Statistics: p-values are calculated using Welch's t-test comparing gene effect scores between wild-type (WT, 0 mutations) and mutated cells (1+2 or 2 mutations). Δ GE = Mean(mutated) − Mean(WT).
0 genes with p < 0.001
| Gene ▼ | N (WT) | Mean GE (WT) | N (1+2) | Mean GE (1+2) | Δ GE | p-value | N (2) | Mean GE (2) | Δ GE (2v0) | p-value (2v0) |
|---|
Low Risk: Exact synonyms from HGNC. Mid Risk: Less certain synonyms. Orthologs: Mouse-to-human gene mappings.
| Input Gene | Status | Official Symbol | Low Risk Synonyms | Mid Risk Synonyms | Orthologs (Mouse→Human) |
|---|---|---|---|---|---|
| Select "Synonym/Ortholog Lookup" mode and click Run | |||||
Run analysis to view summary
